In the game, you have to feed Hank, put him to sleep, and have him use the bathroom. Unlike its two predecessors, there is no "happiness meter." You also have to take pictures of animals and leave food and toys for them.
In My Talking Hank, you have to raise Hank and have him get older. You also have to collect pictures of animals.
The setting of the game is on a Hawaiian island with lots of animals.